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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1949 1
1951 1
1953 2
1956 1
1958 1
1960 1
1961 1
1962 3
1963 3
1964 6
1965 4
1966 5
1967 8
1968 8
1969 15
1970 10
1971 21
1972 12
1973 21
1974 26
1975 74
1976 80
1977 97
1978 91
1979 120
1980 129
1981 176
1982 161
1983 246
1984 268
1985 281
1986 358
1987 340
1988 435
1989 565
1990 657
1991 789
1992 902
1993 990
1994 1200
1995 1553
1996 1748
1997 2050
1998 2404
1999 3023
2000 3529
2001 4054
2002 4454
2003 5096
2004 5891
2005 6855
2006 7629
2007 8662
2008 9599
2009 10412
2010 11080
2011 11725
2012 12603
2013 13098
2014 13486
2015 13796
2016 13438
2017 13169
2018 12893
2019 13575
2020 13814
2021 14176
2022 10814
2023 9570
2024 4197

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237,839 results

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Page 1
Breast cancer genes: beyond BRCA1 and BRCA2.
Filippini SE, Vega A. Filippini SE, et al. Front Biosci (Landmark Ed). 2013 Jun 1;18(4):1358-72. doi: 10.2741/4185. Front Biosci (Landmark Ed). 2013. PMID: 23747889 Free article. Review.
Breast cancer (BC) is a heterogeneous disease. The majority of breast cancer cases (about 70 percent) are considered sporadic. Familial breast cancer (about 30 percent of patients), often seen in families with a high incidence of BC, has been associated with a number of hi …
Breast cancer (BC) is a heterogeneous disease. The majority of breast cancer cases (about 70 percent) are considered sporadic. Famili …
Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression.
Bagot RC, Parise EM, Peña CJ, Zhang HX, Maze I, Chaudhury D, Persaud B, Cachope R, Bolaños-Guzmán CA, Cheer JF, Deisseroth K, Han MH, Nestler EJ. Bagot RC, et al. Nat Commun. 2015 May 8;6:7062. doi: 10.1038/ncomms8062. Nat Commun. 2015. PMID: 25952660 Free PMC article.
Here, we demonstrate that glutamatergic vHIP afferents to NAc regulate susceptibility to chronic social defeat stress (CSDS). We observe reduced activity in vHIP in mice resilient to CSDS. ...These data indicate that vHIP afferents to NAc uniquely regulate susceptibilit …
Here, we demonstrate that glutamatergic vHIP afferents to NAc regulate susceptibility to chronic social defeat stress (CSDS). We obse …
Searching for the major histocompatibility complex psoriasis susceptibility gene.
Capon F, Munro M, Barker J, Trembath R. Capon F, et al. J Invest Dermatol. 2002 May;118(5):745-51. doi: 10.1046/j.1523-1747.2002.01749.x. J Invest Dermatol. 2002. PMID: 11982750 Free article. Review.
Psoriasis, a common skin disorder, is widely regarded to be multifactorial in origin including gene-gene and gene-environment interactions. Genetic and allelic heterogeneity, multifactorial inheritance, and low penetrance of susceptibility alleles subs …
Psoriasis, a common skin disorder, is widely regarded to be multifactorial in origin including gene-gene and gene-envir …
Susceptibility Genes to Plant Viruses.
Garcia-Ruiz H. Garcia-Ruiz H. Viruses. 2018 Sep 10;10(9):484. doi: 10.3390/v10090484. Viruses. 2018. PMID: 30201857 Free PMC article. Review.
Host factors may have antiviral or proviral activities. Proviral factors condition susceptibility to viruses by participating in processes essential to the virus. ...These factors could be targets of gene editing to engineer resistance to plant viruses....
Host factors may have antiviral or proviral activities. Proviral factors condition susceptibility to viruses by participating in proc …
The pathogenesis of systemic lupus erythematosus: Harnessing big data to understand the molecular basis of lupus.
Catalina MD, Owen KA, Labonte AC, Grammer AC, Lipsky PE. Catalina MD, et al. J Autoimmun. 2020 Jun;110:102359. doi: 10.1016/j.jaut.2019.102359. Epub 2019 Dec 2. J Autoimmun. 2020. PMID: 31806421 Review.
Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease that causes damage to multiple organ systems. Despite decades of research and available murine models that capture some aspects of the human disease, new treatments for SLE lag behind other …
Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease that causes damage to multiple organ systems. Despite de …
Impact of Gene-Environment Interactions on Cancer Development.
Mbemi A, Khanna S, Njiki S, Yedjou CG, Tchounwou PB. Mbemi A, et al. Int J Environ Res Public Health. 2020 Nov 3;17(21):8089. doi: 10.3390/ijerph17218089. Int J Environ Res Public Health. 2020. PMID: 33153024 Free PMC article. Review.
Several epidemiological and experimental studies have demonstrated that many human diseases are not only caused by specific genetic and environmental factors but also by gene-environment interactions. Although it has been widely reported that genetic polymorphisms play a c …
Several epidemiological and experimental studies have demonstrated that many human diseases are not only caused by specific genetic and envi …
Germline-focused analysis of tumour-detected variants in 49,264 cancer patients: ESMO Precision Medicine Working Group recommendations.
Kuzbari Z, Bandlamudi C, Loveday C, Garrett A, Mehine M, George A, Hanson H, Snape K, Kulkarni A, Allen S, Jezdic S, Ferrandino R, Westphalen CB, Castro E, Rodon J, Mateo J, Burghel GJ, Berger MF, Mandelker D, Turnbull C. Kuzbari Z, et al. Ann Oncol. 2023 Mar;34(3):215-227. doi: 10.1016/j.annonc.2022.12.003. Epub 2022 Dec 16. Ann Oncol. 2023. PMID: 36529447 Free article.
We applied filters to tumour-detected variants based on variant allele frequency, predicted pathogenicity and population variant frequency. For 58 cancer-susceptibility genes, we then examined the proportion of filtered tumour-detected variants of true germline orig …
We applied filters to tumour-detected variants based on variant allele frequency, predicted pathogenicity and population variant frequency. …
Wheat gene TaS3 contributes to powdery mildew susceptibility.
Li S, Ji R, Dudler R, Yong M, Deng Q, Wang Z, Hu D. Li S, et al. Plant Cell Rep. 2013 Dec;32(12):1891-901. doi: 10.1007/s00299-013-1501-7. Epub 2013 Sep 8. Plant Cell Rep. 2013. PMID: 24013794
Some plant genes that are required for susceptibilities to certain pathogens are known as susceptibility genes or susceptibility factors, whose loss-of-function mutations can confer the plants resistances. ...The suppression of gene TaS3 …
Some plant genes that are required for susceptibilities to certain pathogens are known as susceptibility genes o …
Unbiased forward genetics and systems biology approaches to understanding how gene-environment interactions work to predict susceptibility and outcomes of infections.
Kotb M, Fathey N, Aziz R, Rowe S, Williams RW, Lu L. Kotb M, et al. Novartis Found Symp. 2008;293:156-65; discussion 165-7, 181-3. doi: 10.1002/9780470696781.ch12. Novartis Found Symp. 2008. PMID: 18972751 Review.
Like most human diseases, infectious diseases are effected by complex genetic traits and multiple, interactive environmental and inherent host factors. By linking specific genotypes to disease susceptibility phenotypes we can identify the genetic basis for inter-ind …
Like most human diseases, infectious diseases are effected by complex genetic traits and multiple, interactive environmental and inherent ho …
The search for the gene mutations underlying enterotoxigenic Escherichia coli F4ab/ac susceptibility in pigs: a review.
Schroyen M, Stinckens A, Verhelst R, Niewold T, Buys N. Schroyen M, et al. Vet Res. 2012 Oct 12;43(1):70. doi: 10.1186/1297-9716-43-70. Vet Res. 2012. PMID: 23061722 Free PMC article. Review.
It is assumed that the wild boar was originally ETEC-F4 resistant and that susceptibility towards ETEC arose after domestication. There are different phenotypes in the pig determined by which of the three existing F4 variants (F4ab, F4ac or F4ad) they are susceptible …
It is assumed that the wild boar was originally ETEC-F4 resistant and that susceptibility towards ETEC arose after domestication. The …
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